Dataset Archive

Figure 7. Pacer expression promotes formation of WIPI2 puncta upon depolarization.

Figure 6. pRAB7A-dependent function of Pacer in mitophagosome expansion.

Figure 5. Pacer is a pS72 RAB7A-dependent activator of mitophagy.

Figure 4. The Pacer RH domain basic triad controls subcellular localization.

Figure 3. pRAB7A binding preferences dictate subcellular localization.

Figure 1. Rubicon depletion promotes bulk autophagy and Parkin mitophagy.

Figure S2. pS72 Rab7 formation following depolarization, starvation, and iron chelation.

Western blot and gel source data.

Figure S4. MW verification of HaloTag flux reporters.

Figure S3. Immunofluorescence of mitochondria alongside LC3B.

This dataset contains recordings of single-unit activity from multiple brain areas, including globus pallidus-internus (GPi), ventrolateral nucleus of the thalamus (VLa and VLp), and the arm-related regions of the primary motor cortex, including sulcus (M1-S) and gyrus (M1-G) subregions, in monkeys performing a choice reaction time reaching task.

Datasets for Erb et al 2024 "Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities."

Image distortion data associated with the manuscript "An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys."

EMG data from the manuscript, "An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys."

The files found here contain source data, supplementary data, a key resource table, and a list of primers related to the publication "Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson's GBA-N370S mutation."

RASP: A new method for single puncta detection in complex cellular backgrounds_data.

Super-resolution and single-molecule microscopy are increasingly applied to complex biological systems. A challenge of this approach is that fluorescent puncta must be detected in low signal, high noise, and heterogeneous background environments of cells and tissue. The authors present RASP, Radiality Analysis of Single Puncta, a bioimaging-segmentation method that solves this problem.

This digital pathology resource contains digital whole slide images from Lewy body disorders: Parkinson’s disease, Parkinson’s disease with dementia, dementia with Lewy bodies, and control cases.

Source data and code from dopamine neuron activity encode the length of upcoming contralateral movement sequences by Mendonça et al 2024.