Catalog

ASAP is committed to accelerating the pace of discovery and informing a path to a cure for Parkinson’s disease through collaboration, research-enabling resources, and data sharing. We’ve created this catalog to showcase the research outputs and tools developed by ASAP-funded programs.

Dataset

Cryo-ET of S. cerevisiae during starvation (tomograms)

Cryo-ET of S. cerevisiae during starvation (tomograms). Accession number:
https://www.ebi.ac.uk/emdb/EMD-15526
https://www.ebi.ac.uk/emdb/EMD-15545
https://www.ebi.ac.uk/emdb/EMD-15546
https://www.ebi.ac.uk/emdb/EMD-15547
https://www.ebi.ac.uk/emdb/EMD-15549
https://www.ebi.ac.uk/emdb/EMD-15548

Dataset

Global lipidomics of WT and GRN-/- cells & mouse models, including plus and minus GRN addback

This dataset contains:
– Global lipidomics of WT and GRN-/- HeLa cells, including plus and minus GRN addback.
– Global lipidomics of WT and NPC1-/- HeLa cells.
– Global lipidomics of WT and GRN-/- HeLa cells, including plus and minus GRN addback.
Global lipidomics of WT and GRN mutant mouse brain tissue.
https://www.nature.com/articles/s41467-022-33500-9

Dataset

Raw tomogram of a TauRD-YFP aggregate in a TauRD-YFP expressing HEK293T cells and primary mouse neurons

Raw tomogram of a TauRD-YFP aggregate in a TauRD-YFP expressing Hek293T cells.
Accession numbers:
HEK293T:
https://www.ebi.ac.uk/emdb/EMD-13739
Primary mouse neurons:
https://www.ebi.ac.uk/emdb/EMD-13740

Dataset

Proteomics of iNeurons or HeLa cells with or without FBXO7

TMT proteomics datasets from FBXO7-/- hESC differentiation to iNeurons and HeLa cells.

Dataset

The mass spectrometry proteomics data associated of TauRD-Y interactome from TauRD-Y and TauRD-Y* cells

The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE84 partner repository with the dataset identifier PXD023400. Associated with the following preprint: Saha et al., 2022 (published on biorxiv on February 19, 2022). https://www.biorxiv.org/content/10.1101/2022.02.18.481043v1.full

Dataset

Tomogram data of TauRD-Y forms amyloid-like aggregates in cells

Tomograms: The tomograms shown in Fig. 1d and Fig. 3c are available in the EMDB https://www.ebi.ac.uk/emdb/ through the following information: EMD ID: EMD-13739 (Fig. 1d) and EMD-13740 (Fig. 3c)
https://www.ebi.ac.uk/emdb/EMD-13739
https://www.ebi.ac.uk/emdb/EMD-13740
Associated with the following preprint: Saha et al., 2022 (published on biorxiv on Feb 19th, 2022) https://www.biorxiv.org/content/10.1101/2022.02.18.481043v1.full