Dandiet: Astrocytes mediate the dopaminergic modulation of tonic GABAergic signaling in Substanta nigra
By onThis is a Dandiet that hosts binary files of electrophysiology data for the titled manuscipt 'Astrocytes mediate the dopaminergic modulation of tonic GABAergic signaling in Substanta nigra'.
Fushiki et al – Video Recording of Parkinson’s Disease Model Mice
By onRaw behavioral datasets and experimental video recordings referenced in the ).
Imaging Dataset for: A Vulnerable Subtype of Dopaminergic Neurons Drives Early Motor Deficits in Parkinson’s Disease
By onDataset includes imaging data from experiments detailed in PMID: 39763754. Coronal brain sections imaged with fluorescence microscopy to assess reporter and transgene expression.
EMG fabrication in Rodrigues-Vaz & Athalye et al
By onThis is the protocol for fabrication of EMG electrodes for bulk muscle recordings used for Rodrigues-Vaz and Athalye et al, 2025 and based on Akay et al, 2006.
Histology from Rodrigues-Vaz and Athalye et al: Imaging of specific mouse brain region where viral injection and implant was placed at
By onThis dataset is part of an experiment in which dorsolateral striatum (DLS) was imaged while mice performed task. This images show targeting of viral expression and lens implant to DLS.
Virus Injections from Rodrigues-Vaz & Athalye et al
By onThis is the standard stereotaxic/Nanoject injection mouse surgery protocol for Rodrigues-Vaz and Athalye et al, 2025.
Code used to analyze striatum population dynamics during isometric forelimb actions
By onCode used for analysis and figures for paper titled: "Striatal ensembles specify and control granular forelimb actions".
2-photon imaging raw data from striatal populations through GRIN lens
By onThe neuronal activity of striatal cells was acquired while the mouse performed a two-action isometric forelimb force task.
Holographic stimulation of neuronal ensembles in striatum
By onThis dataset includes all the raw data regarding the experiments with 2-photon imaging, isometric force task and holographic stimulation in Rodrigues-Vaz & Athalye et al.
NERINE reveals rare variant associations in gene networks across phenotypes and implicates an SNCA-PRL-LRRK2 subnetwork in Parkinson’s disease
By onNERINE is a rare variant association test that links rare genetic variation with gene network topology to improve discovery power in complex diseases. NERINE implicates an α-synuclein/prolactin stress-response in Parkinson’s disease.
all protocols related to “Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency”
By onAll protocols related to "Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency"
Regulation of the proteasome 20S core particle by the Parkinsonism-associated Proteins FBXO7 and PI31
By onGenetic forms of PD are associated with variants in FBXO7 and PI31. Combining biochemical and structural approaches, we describe the proteasome interaction of these proteins and map disease variants to disruption of proteasome interaction.
Cell-autonomous and non-cell-autonomous drivers of dopamine neuron vulnerability in Parkinson’s disease
By onThis review examines evidence for cell-autonomous mechanisms and non-cell-autonomous processes arising from glial and peripheral immune cells and how these pathways can converge to create chronic cellular stress and trigger cell death mechanisms.
TEsingle Software
By onSoftware to analyze TE expression in single cell/single nuclei RNA-seq datasets.
TEsingle pipeline for analysis of Martirosyan dataset
By onCode to analyze Martirosyan et al. substantia nigra single nuclei RNA-seq dataset with TEsingle.
TEsingle benchmarking pipeline
By onCode to perform benchmarking of simulated single cell/nuclei RNA-seq datasets with TEsingle and other scRNA-seq software.
Simulation data for TEsingle benchmarking
By onThis dataset includes files for benchmarking analysis with TEsingle and other snRNA tools, facilitating reproducibility.
Fluorescence-Gated Flow Cytometry Approach for Measuring Lipid Flippase Activity in Mammalian Cells
By onP4-ATPase lipid flippases create lipid asymmetry in cells. A new strategy using NBD-lipid uptake assays improves sensitivity and analysis of ATP11C function. This method enhances studying regulatory interactions in mammalian cells.
Data and code for Active Escape (“Integrated Representations of Threat and Control in the Lateral Frontal Pole”)
By onData, Code, and Key Resource Table used in the preprint from Stasiak et al., 2025 ("Integrated Representations of Threat and Control in the Lateral Frontal Pole").
Active Escape Protocol (Stasiak et al., 2026)
By onProtocol for Active Escape task by Stasiak et al., referenced in "Integrated Representations of Threat and Control in the Lateral Frontal Pole" (2026) manuscript.
