Available at Jax: SNV/WT, SNV/SNV, and REV/REV of the R42P PRKN variant. Associated with Parkinson's Disease with dementia. Parental line is KOLF2.1J (JIPSC1000)
Study explores transposable elements role in Parkinson's disease neuroinflammation. TE activation in specific brain regions correlates with innate immune responses, indicating potential involvement in chronic neuroinflammation and PD progression.