Datasets and Key Resources Table used in Stedehouder & Roberts (2024) “Rapid modulation of striatal cholinergic interneurons and dopamine release by satellite astrocytes”
By onThis repository contains a Key Resources Table with details on lab materials and the persistent identifiers for protocols and code used and generated in this study; and tabular datasets shown in main and supplementary figures.
Datasets and Key Resources Table used in Zang, Y. et al. (2025) “An axonal brake on striatal dopamine output by cholinergic interneurons”
By onThis repository contains a 1) Key Resources Table with details on key resources and the persistent identifiers for protocols and code used and generated in this study; 2) Source Data Folder, and 3) Supplementary Data Folder.
Electrophysiological validation of striatal neurons and dopamine neurons in D1-Cre, A2a-Cre, D1-FlpO, A2a-FlpO, DAT-FlpO transgenic mice
By onElectrophysiology dataset from whole-cell recordings from murine striatal spiny projection and midbrain dopaminergic neurons from acute slices prepared from knock-in transgenic mouse lines: D1-Cre- A2a-Cre- D1-FlpO- A2a-FlpO- DAT-FlpO.
Dataset for Article “Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors”
By onPrimary Dataset for article by Nielsen et al "Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA–induced dyskinetic behaviors"
Primary Data for Article “Postsynaptic adaptations in direct pathway muscarinic M4-receptor signaling follow the temporal and regional pattern of dopaminergic degeneration”
By onPrimary Data for Article "Postsynaptic adaptations in direct pathway muscarinic M4-receptor signaling follow the temporal and regional pattern of dopaminergic degeneration"
Dataset for Article “Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories”
By onDataset for Article "Corticonigral projections recruit substantia nigra pars lateralis dopaminergic neurons for auditory threat memories"
Simulated mouse primary motor cortex activity during control and decreased pyramidal tract neuron excitability in the parkinsonian condition
By onSixteen files were collected from 4 sets of simulations, each with control and Parkinsonian conditions in rest and activated states. Parkinsonian M1 simulations showed reduced PT5B neuron excitability. Simulations lasted 4.3 seconds.
FSCV dopamine, spike, and LFP data used for validating chronic electrode implanted in aseptic semi-sealed chamber
By onFSCV dopamine, spike, and LFP data used for validating chronic electrode implanted in aseptic semi-sealed chamber in Choi et al. 2025 JNeurosciMethods.
MatLab Code and Source Data for Analyzing Reach-related Single Unit Activity in the Internal Segment of the Globus Pallidus in Parkinsonian Macaque
By onSource data stored in a non-proprietary format, all MATLAB code, along with histology data prepared for the publication of our study on movement-related activity in the internal globus pallidus of parkinsonian macaques (Kase et al. 2025).
Source data for Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation
By onChen et al (2024) study links α-synuclein aggregation to hyperexcitability in motor cortical neurons.
Source data for the article “α-Synuclein aggregation decreases cortico-amygdala connectivity and impairs social behavior in mice”
By onα-Synuclein aggregation in mice reduces cortico-amygdala connectivity, leading to impaired social behavior.
LRRK2-mutant microglia and neuromelanin synergize to drive dopaminergic neurodegeneration in an iPSC-based Parkinson’s disease model
By onPD is a neurodegenerative disorder characterized by the loss of neuromelanin (NM)-containing dopamine neurons. This work highlights NM-activated microglia’s role in PD progression, and provides a model for testing therapeutic targets.
Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson’s disease
By onNeuromelanin (NM) is pigment accumulating with age in human SNpc dopamine (DA) neurons. This study discloses unrealized NM effects within nigral DA neurons, advancing our comprehension of sex-specific features shaping sex-biased vulnerability to PD.
Generation of knock-in Cre and FlpO mouse lines for basal ganglia and dopamine neuron investigation (SOURCE DATA)
By onThe dataset contained in this repository are the processed data and information used in all the quantifications, tables, and figures associated with the project by Albarran et al 2025 elife.
Dataset for Article “Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum” by Brill-Weil et al
By onDopaminergic neuron axons have GABAARs and nAChRs that influence DA release. GABAAR antagonism enhances nAChR activity, while picrotoxin inhibits nAChRs, revealing GABAARs' role in regulating nicotinic input onto DA axons.
