Autophagosome live cell imaging
By onAutophagosome live cell imaging for the quantification of PINK-PARKIN mitophagy.
Figure 4: The Pacer RH domain basic triad controls subcellular localization [FINAL]
By onFigure 4. The Pacer RH domain basic triad controls subcellular localization.
Figure 3: Rubicon – Rab7 binding colocalization [FINAL] Creators
By onFigure 3. pRAB7A binding preferences dictate subcellular localization.
Figure 7. Pacer expression promotes formation of WIPI2 puncta upon depolarization [FINAL]
By onFigure 7. Pacer expression promotes the formation of WIPI2 puncta upon depolarization.
Figure 6: Pacer LC3B imaging [FINAL]
By onFigure 6. pRAB7A-dependent function of Pacer in mitophagosome expansion.
Figure S3: Immunofluorescence of mitochondria alongside LC3B [FINAL]
By onSource Data for Figure S3 in https://doi.org/10.1083/jcb.202309015.
Figure S2. pS72 Rab7 formation following depolarization, starvation, and iron chelation [FINAL]
By onFigure S2. pS72 Rab7 formation following depolarization, starvation, and iron chelation.
Gradient-index (GRIN) lens implantation surgery in non-human primates
By onProcedures involve injecting AAV-GCaMP6 into the SMA of non-human primates for calcium imaging experiments. A GRIN lens is then inserted into the injected area, protected by a custom chamber with a lid for reuse.
Reward perseveration is shaped by GABAA-mediated dopamine pauses: Histology from Behavior Data Mice
By onRaw images and fluorescence analysis for mouse tissue sections in the different cohorts are stored in separate zip files. Behavior_summary_data_HTP_Histology.csv summarizes fluorescence quantification per animal
Colocalisation imaging of endogenous TMEM192 with lysosomal and mitochondria markers
By onThe authors describe a method that can be used to verify the correct localisation of endogenously expressed TMEM192, by assessing their colocalization with LAMP1 (a lysosomal marker) and ATPB1 (a mitochondrial marker).
Ex vivo mouse brain patch clamp recordings combined with optogenetic stimulation
By onIn this protocol, the authors detail the steps to perform ex-vivo brain slice electrophysiology and optogenetic stimulation.
Immunofluorescence for confocal imaging after slice recording
By onThis protocol describes the steps for immunostaining and confocal imaging of ex vivo slices following an electrophysiological experiment.
Micro-PET CT procedures for brain imaging of rats
By onMicro-PET CT procedures for brain imaging of rats.
Refinement of efficient encodings of movement in the dorsolateral striatum throughout learning (DATA)
By onLocomotion velocity (rod encoder) and calcium imaging data were used in the research publication, "Refinement of efficient encodings of movement in the dorsolateral striatum throughout learning" by Jaidar and Albarran et al., 2024.
SoCal Kinesia and Incentivization for Parkinson’s Disease (SKIP): Active Escape
By onThe Active Escape Task from the Socal Kinesia and Incentivization for Parkinson's Disease (SKIP) dataset. This task includes shock threats and controllability variations to explore incentive effects on movement.
SoCal Kinesia and Incentivization for Parkinson’s Disease (SKIP): Approach-Avoid
By onThe Approach-Avoid Task from the Socal Kinesia and Incentivization for Parkinson's Disease (SKIP) dataset. Participants reach towards or away from emotional images based on valence, creating congruent and incongruent emotion-action conditions.
SoCal Kinesia and Incentivization for Parkinson’s Disease (SKIP): Ultra-High Field Functional Connectivity
By onHuman Ultra-High Field Functional Connectivity data from the Socal Kinesia and Incentivization for Parkinson's Disease (SKIP) dataset.
SoCal Kinesia and Incentivization for Parkinson’s Disease (SKIP): Incentivized Reaching
By onIncentivized Reaching from The Socal Kinesia and Incentivization for Parkinson's Disease (SKIP) dataset, which focuses on human movement and the modulatory impact of incentivization, specifically in the context of Parkinson's disease.
