Christos Proukakis is a practicing clinical academic neurologist, currently a Professor of Neurology and Neurogenetics in the University College London Institute of Neurology, and Honorary Consultant Neurologist. His clinical and research focus is Parkinson’s disease / synucleinopathies. He hypothesized and is investigating the role of somatic mutations in the brain in these. His lab demonstrated somatic copy number gains (CNVs) in the alpha-synuclein gene, and produced the first genome-wide somatic CNV calls in synucleinopathy brain using single cell whole genome sequencing in MSA. He is also using other novel genetic analysis technologies, such as long-read sequencing for the difficult GBA gene.
Co-PI (Core Leadership)
Christos Proukakis, PhD
University College London
Christos Proukakis is a practicing clinical academic neurologist, currently a Professor of Neurology and Neurogenetics in the University College London Institute of Neurology, and Honorary Consultant Neurologist. His clinical and research focus is Parkinson’s disease / synucleinopathies. He hypothesized and is investigating the role of somatic mutations in the brain in these. His lab demonstrated somatic copy number gains (CNVs) in the alpha-synuclein gene, and produced the first genome-wide somatic CNV calls in synucleinopathy brain using single cell whole genome sequencing in MSA. He is also using other novel genetic analysis technologies, such as long-read sequencing for the difficult GBA gene.
