This study employs a novel drug targeting technology DART(drug acutely restricted by tethering), to selectively block GABAA receptors on VTADA neurons as mice engage in Pavlovian learning.
Population-scale, disease-context aware meta single-nucleus eQTLs mapping (N = 1,197) in nine cell types from cortex and substantia nigra identifies 125 risk genes and cell types for PD GWAS signals.
Guide for analyzing for analysis of synaptic loci density and pre- and postsynaptic volumes (SynDOVE). from confocal images of pre- and postsynaptic loci in fixed brain sections with Imaris software.
