6-OHDA mouse model of Parkinson’s disease

Output Details

This protocol describes the steps for generating a 6-hydroxy-dopamine (6-OHDA) mouse model of Parkinson's disease. Low or high doses of 6-OHDA are injected into the medial forebrain bundle to induce a partial or a more complete dopaminergic lesion respectively.
Tags
  • 6-OHDA
  • Animal
  • Animal models
  • Mouse

Meet the Authors

  • Beatriz Elizabeth Nielsen, PhD

    Key Personnel: Team Edwards

    University of Colorado Anschutz Medical Campus

  • Chris Ford, PhD

    Collaborating PI: Team Edwards

    University of Colorado