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Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
Output Details
Description
This repository contains analysis code for the publication found here, which explored the response of astrocytes, neurons and astro-neuronal co-cultures to alpha-synuclein oligomers.
The analysis includes work shared between two repositories:
This current repository contains single cell and bulk RNA-sequencing analysis of the cell culture models utilised in the study.
The repository at https://github.com/aaronwagen/Astrocytes_editing contains the analysis of RNA editing in the cell culture models, as well as in a published dataset of post-mortem brain samples.