Calf intestine alkaline phosphatase (CIAP) treatment

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Description

Alpha-synuclein phosphorylated at serine 129 (PSER129) occurs in two pools, non-aggregated (physiological) and aggregated (disease). This protocol allows for the selective dephosphorylation of non-aggregated PSER129 and enhances the specificity and sensitivity immunodetection of aggregated PSER129. Thus, this protocol can be used to differentiate physiological from aggregated PSER129.

Identifier (DOI)

10.17504/protocols.io.5qpvoky7bl4o/v1

Team

Team Kordower

Program

Collaborative Research Network

Theme

Neuro-Immune Interactions

Meet the Authors

Bryan A. Killinger

External Collaborator
Solji Choi

External Collaborator

Calf intestine alkaline phosphatase (CIAP) treatment

Output Details

Meet the Authors

Bryan A. Killinger

Solji Choi

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