Collection of protocols for paper: "Glucocerebrosidase, a Parkinson´s disease-associated protein, is imported into mitochondria and regulates complex I assembly and function"

Description

This is a collection of protocols used in a recent pre-print by the Deleidi Lab, Team Schapira. You can access pre-print at https://doi.org/10.21203/rs.3.rs-1521848/v1. This is relevant to the pre-print publication https://hub.asap.science/shared-research/e4c58c5f-d833-4ed3-81a8-e3ee96094799/edit

Identifier (DOI)

10.17504/protocols.io.8epv593dng1b/v1

Tags

Differentiation
GCase activity
Human
In Vitro
iPSC
Midbrains
Organoid
Plasmids
Single-cell analysis

Team

Team Schapira

Program

Collaborative Research Network

Theme

Neuro-Immune Interactions

Meet the Authors

Michela Deleidi, MD, PhD

Co-PI (Core Leadership): Team Schapira,

Institut Imagine
Maria Jose Perez Jimenez, PhD

Key Personnel: Team Schapira,

German Center for Neurodegenerative Diseases
Hariam Raji

External Collaborator
Federico Bertoli, MD

Key Personnel: Team Schapira,

German Center for Neurodegenerative Diseases
Pascale Baden

External Collaborator

Collection of protocols for paper: “Glucocerebrosidase, a Parkinson´s disease-associated protein, is imported into mitochondria and regulates complex I assembly and function”

Output Details

Meet the Authors

Michela Deleidi, MD, PhD

Maria Jose Perez Jimenez, PhD

Hariam Raji

Federico Bertoli, MD

Pascale Baden

Related Research

Glucocerebrosidase, a Parkinson´s disease-associated protein, is imported into mitochondria and regulates complex I assembly and function

Glucocerebrosidase is imported into mitochondria and preserves complex I integrity and energy metabolism

Formation of ventral midbrain Assembloid/Organoids