A study on Parkinson's disease links gut microbiome to brain health. Analysis of 490 PD patients and 234 controls reveals dysbiosis, microbial clusters, and disease-promoting factors in PD microbiome, offering insights for future research.
Parkinson's disease is a fast-growing neurologic disease with no known prevention. Environmental factors like head trauma in sports/combat and pesticide exposure contribute significantly to the disease, suggesting preventable causes for some cases.
Zenodo archive contains post-sequence QC, taxonomic, and functional profiling data. Supplementary Code includes workflow and bioinformatic processing used in the manuscript. Raw sequences and metadata are on NCBI SRA under BioProject ID PRJNA834801.