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Genome-wide Analysis of Motor Progression in Parkinson Disease
Published November 1, 2022
Output Details
Preprint November 11, 2022
Published November 1, 2022
Description
The genetic basis of Parkinson disease (PD) motor progression is largely unknown. Previous studies of the genetics of PD progression have included small cohorts and shown a limited overlap with genetic PD risk factors from case-control studies. Here, we have studied genomic variation associated with PD motor severity and early-stage progression in large longitudinal cohorts to help to define the biology of PD progression and potential new drug targets.
Identifier (DOI)
10.1212/NXG.0000000000200092