H9 ES AAVS1-NGN2 FAM134C-/-

By Melissa Hoyer, PhD and J. Wade Harper

Output Details

Description
ES cells for making iNeurons lacking the ER-phagy receptor FAM134C PubMed=37425907; Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent  cell line). Knockout cell: Method=CRISPR/Cas9; 27258; RETREG3. Transfected with: HGNC; 13805; NEUROG2. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. NCBI_TaxID=9606; ! Homo sapiens (Human) RRID:CVCL_C4EK ! H9 AAVS1-TRE3G-NGN2 Female Blastocyst stage Embryonic stem cell
Tags
  • Endoplasmic reticulum
  • Human
  • Stem cells – embryonic
Team
Team Harper
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

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