HeLa HFT/TO PARK2 FBXO7−/−
Output Details
Description
HeLa cells in which FBXO7 has been deleted using CRISPR
Tags
- Human
- Mitophagy
Meet the Authors
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Jiuchun Zhang
External Collaborator
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Related Research
PARK15/FBXO7 is dispensable for PINK1/Parkin mitophagy in iNeurons and HeLa cell systems
PINK1 and Parkin promote damaged mitochondria removal through Ub phosphorylation, Parkin activation. FBXO7 mutation in PD may not affect mitophagy in HeLa and neuron cells, suggesting it may not play a significant role in Parkin-dependent mitophagy.
Human microscopy images
FISH labelling of brain tissue using different markers in adult human brain sections.
Alphafold predictions for GolgiFold Protein-Protein Interactions
This entry is all the pairwise Alphafold models in GolgiFold as a web viewer.