Identification of global proteome changes upon DFP treatment of HeLa cells

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Description

We aimed to identify proteins that would be turned over upon DFP treatment, a small molecule that mimicks hypoxia treatment and which induces NIX/BNIP3 mitophagy. We aimed to identify which proteins are degraded upon 24 h DFP treatment and verified whether there was an enrichment of mitochondrial proteins being selectively turned over by mitophagy under these conditions.

Tags

Human
In Vitro
Mass spectrometry

Team

Team Hurley

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Markus Hartl

External Collaborator

Identification of global proteome changes upon DFP treatment of HeLa cells

Output Details

Meet the Authors

Markus Hartl

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