Actively transcribed messenger ribonucleic acids (mRNAs) were harvested from SNc dopaminergic neurons in aSYN monomer or PFF-injected mice 12 weeks post injection and then subjected to RNASeq analysis.
The novel model of AOF successfully replicates the human peri- and post-menopause stages, including erratic estrous cycles and hormone fluctuations, followed by undetectable estrogen levels.
