Motor cortical regions have undergone evolutionary expansion and specialization from rodents to primates. Studying these regions in non-human primates (NHPs) is relevant to understanding motor control in NHP models of movement disorders.
A workflow using ImageJ/FIJI aims to create three-slice MIPs from multi-series .czi files to capture weak signals. It involves extracting datasets, creating projections, and saving images for efficient analysis in CellProfiler.
Immune system activation may contribute to PD development. Infection increases BBB permeability in mice, leading to brain inflammation. This suggests infections could trigger PD in genetically susceptible individuals.