More of less: Novel multi-ome profiling of single human neurons

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Published March 8, 2022

Epigenetic modifications to DNA and chromatin interact to influence gene expression and cellular phenotypes, but defining these omics layers in complex tissues is a daunting task. In this issue of Cell Genomics, Luo et al. describe a novel single-cell multi-omic method, simultaneously profiling transcriptome, DNA methylome, and chromatin accessibility, to shed light on human neurons.
Tags
  • Brief Communication
  • Epigenomics
  • Nucleosome, methylation and transcription sequencing-sequencing (NMT-seq)

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