More of less: Novel multi-ome profiling of single human neurons

Description

Epigenetic modifications to DNA and chromatin interact to influence gene expression and cellular phenotypes, but defining these omics layers in complex tissues is a daunting task. In this issue of Cell Genomics, Luo et al. describe a novel single-cell multi-omic method, simultaneously profiling transcriptome, DNA methylome, and chromatin accessibility, to shed light on human neurons.

Identifier (DOI)

10.1016/j.xgen.2022.100110

Tags

Brief Communication
Epigenomics
Nucleosome, methylation and transcription sequencing-sequencing (NMT-seq)

Team

Team Voet

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Huiwen Che

Key Personnel: Team Voet,

KU Leuven
Bernard Thienpont, PhD

Co-PI (Core Leadership): Team Voet,

KU Leuven

More of less: Novel multi-ome profiling of single human neurons

Output Details

Meet the Authors

Huiwen Che

Bernard Thienpont, PhD

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