Aligning Science Across Parkinson's Logo Text

Mouse Ovariectomy

By Sabina Marciano, Roberta Marongiu, PhD
View Published Protocol

Output Details

Description
This protocol describes the steps to perform an ovariectomy in a mouse. This procedure is used to induce menopause.
Identifier (DOI)
10.17504/protocols.io.14egn338zl5d/v1
Tags
  • Estrogen
  • Menopause
  • Other
Team
Team Kaplitt
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

Related Research

Accelerated Ovarian Failure AOF mouse model: a model of transitional menopause

The novel model of AOF successfully replicates the human peri- and post-menopause stages, including erratic estrous cycles and hormone fluctuations, followed by undetectable estrogen levels.

View Protocol

RNA Seq dataset for: α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease

Actively transcribed messenger ribonucleic acids (mRNAs) were harvested from SNc dopaminergic neurons in aSYN monomer or PFF-injected mice 12 weeks post injection and then subjected to RNASeq analysis.

View Dataset

RNAScope in situ hybridization (ISH) multiplex fluorescent

Instructions to perform ISH using RNAscope kit from ACDBio company optimized for frozen mouse brain and nodose ganglia sections.

View Protocol
View More Outputs
Aligning Science Across Parkinson's
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.