Cre-dependent expression of human tyrosinase induces the formation of neuromelanin in catecholaminergic neurons. The CbH promoter is a strong, pan-neuronal, non-silencable promoter.
Two rhesus macaques were tested with AAVrg-hSyn-mCherry in the putamen, showing numerous mCherry-positive neurons in motor cortical regions projecting to the putamen.
