The secretion of endogenous α-syn mediated by DNAJC5 is found in a human neuroblastoma cell line, The authors propose that DNAJC5 forms a palmitoylated oligomer to accommodate and export α-syn.
The 5-HT4R agonist RS67333 modulates striatal acetylcholine and dopamine release through acetylcholinesterase inhibition, not 5-HT4R activation, highlighting its potential as an AChE inhibitor for brain disorders.
This repository contains: 1) Key Resources Table containing details on key resources and the persistent identifiers for protocols and code used and generated in this study; 2) Source Data; and 3) README file.