PD5D long read DNA-seq

Description

This dataset contains CCS corrected HiFi long-read DNA sequencing (lrDNAseq) in FASTQ format for 100 PMDBS samples from Parkinson's patients and healthy controls. It's part of the PD5D atlas, where the same subjects were also profiled with other omics assays including genotyping, single-cell ATACseq, and spatial transcriptomics.

Identifier (DOI)

10.5281/zenodo.19124632

Tags

Human
Long-read sequencing
Post-mortem brain tissues
Postmortem

Discovery Team

Team Scherzer

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Kwanho Kim

External Collaborator
Zechuan Lin

External Collaborator
Sean Simmons

External Collaborator
Jacob Parker

External Collaborator
Matthew Kearney

External Collaborator
Zhixiang Liao

External Collaborator
Nathan Haywood

External Collaborator
Jixiang Zhang

External Collaborator
Madison Cline

External Collaborator
Idil Tuncali

External Collaborator
Monika Sharma

External Collaborator
Geidy Serrano

External Collaborator
Thomas Beach

External Collaborator
Xianjun Dong, PhD

Co-PI (Core Leadership): Team Scherzer,

Yale University
Popic Victoria

External Collaborator
Clemens Scherzer, MD

Lead PI (Core Leadership): Team Scherzer,

Brigham & Women's Hospital
Joshua Levin, PhD

Co-PI (Core Leadership): Team Scherzer,

Broad Institute