PD5D midbrain single-nucleus RNA-seq hybrid selection

By Kwanho Kim, Zechuan Lin, Sean Simmons, Jacob Parker, Matthew Kearney, Nathan Haywood, Jixiang Zhang, Zhixiang Liao, Madison Cline, Idil Tuncali, Monika Sharma, Geidy Serrano, Thomas Beach, Xianjun Dong, PhD, Popic Victoria, Clemens Scherzer, MD, Joshua Levin, PhD

View Published Dataset

Description

This dataset contains raw FASTQ files from the midbrain single-nucleus RNA sequencing (snRNAseq) dataset with hybrid selection for the matching PMDBS samples from the PD5D chort. The same subjects were also profiled with other omics assays including genomic DNAseq, genotyping, single-cell ATACseq, and spatial transcriptomics. >

Identifier (DOI)

10.5281/zenodo.19124469

Tags

Human
Postmortem
RNA Single Cell
snRNA-seq (Single-nuclear RNA-seq)

Discovery Team

Team Scherzer

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Kwanho Kim

External Collaborator
Zechuan Lin

External Collaborator
Sean Simmons

External Collaborator
Jacob Parker

External Collaborator
Matthew Kearney

External Collaborator
Nathan Haywood

External Collaborator
Jixiang Zhang

External Collaborator
Zhixiang Liao

External Collaborator
Madison Cline

External Collaborator
Idil Tuncali

External Collaborator
Monika Sharma

External Collaborator
Geidy Serrano

External Collaborator
Thomas Beach

External Collaborator
Xianjun Dong, PhD

Co-PI (Core Leadership): Team Scherzer,

Yale University
Popic Victoria

External Collaborator
Clemens Scherzer, MD

Lead PI (Core Leadership): Team Scherzer,

Brigham & Women's Hospital
Joshua Levin, PhD

Co-PI (Core Leadership): Team Scherzer,

Broad Institute