POLCAM is a simplified single-molecule orientation localization microscopy method, using a polarization camera, enabling fast easy implementation on fluorescence microscopes. Here, we apply it to alpha-synuclein fibrils.
This study shows that genes linked to brain diseases like Alzheimer’s and Parkinson’s act through the immune system outside the brain, with effects varying by ancestry. It highlights the need for ancestry-specific genetic studies.
ASAP CRN Cloud released version 4.0.0 with expanded datasets including Human Postmortem-derived Brain Sequencing and Mouse datasets. New collections and individual datasets were added, enhancing PMDBS and Mouse RNA sequencing data.
