Mutations in ATP13A2 gene can cause familial Parkinson's disease. Deleting ATP13A2 in adult mice leads to dopaminergic nerve terminal loss and neuronal degeneration, mimicking symptoms of ATP13A2-related neurodegenerative diseases.
Dataset from ESRF's ID16A beamline includes high-res X-ray nano-tomography data of human brain samples with Alzheimer’s, Parkinson’s, and control cases, along with acquisition details for reuse.
Dataset from DESY, GINX Beamline, Germany offers X-ray phase-contrast tomography volumes of human brain tissue for 3D analysis and reproducible imaging workflow correlation with histological sections.