Rating of levodopa-induced dyskinesia in 6-OHDA lesioned mice

Research Community
Research Community

ASAP supports three programs and serves as a member of multiple consortia to advance research for the benefit of the global Parkinson’s disease community.
Explore
Highlights
Highlights

ASAP shares the impact that our initiative, network, and supported programs have had on providing new insights into Parkinson’s disease. Discover news, interviews, awards, and annual impact.
Explore
Open Science
Open Science

ASAP is dedicated to facilitating a research environment where meaningful collaboration, research-enabling resources, and data sharing provides the answers we need to understand, diagnose, and treat Parkinson’s disease. Discover our open science philosophy.
Explore
Tools & Resources
Tools & Resources

ASAP is committed to developing and openly sharing research outputs, including data, code, protocols, and key lab materials, to help the scientific community build upon existing work.
Explore

Description

This protocol describes scoring of abnormal involuntary movements (AIMs), the behavioral manifestation of levodopa-induced dyskinesia, in 6-OHDA lesioned mice.

Identifier (DOI)

10.17504/protocols.io.5jyl8dm8rg2w/v1

Tags

Activity Assay
Behavioral
Behavioral annotation
Dyskinesia

Team

Team Surmeier

Program

Collaborative Research Network

Theme

Circuitry and Brain-Body Interactions

Meet the Authors

Beatriz Elizabeth Nielsen, PhD

Key Personnel: Team Edwards,

University of Colorado Anschutz Medical Campus
Shenyu Zhai, PhD

Key Personnel: Team Surmeier,

Northwestern University

Rating of levodopa-induced dyskinesia in 6-OHDA lesioned mice

Output Details

Meet the Authors

Beatriz Elizabeth Nielsen, PhD

Shenyu Zhai, PhD

Related Research

EMG recordings-Rodrigues-Vaz and Athalye et al, 2025

Dephosphorylation of phosphorylated Rab GTPases by PPM phosphatases

GCase assay – Resorufin β-D-glucopyranoside