Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease: Bioinformatic Prioritisation and Hit Validation

Output Details

This protocol describes the Bioinformatic Prioritisation of PD GWAS candidates for High Content Screening, and Hit Validation by allele-specific expression (ASE) analysis.
Tags
  • High Content Screening
  • Parkinson's disease
  • Substantia nigra

Meet the Authors

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    Karishma D’Sa, MSc

    Key Personnel: Team Wood Team Hardy

    University College London

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    Sebastian Guelfi

  • David Zhang, MSc

    Key Personnel: Team Wood

    University College London

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    Alan Pittman

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    Daniah Trabzuni

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    Demis A. Kia

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    Nicholas W Wood

  • John Hardy, PhD

    Lead PI (Core Leadership): Team Hardy

    University College London

  • Claudia Manzoni, PhD

    Key Personnel: Team Hardy

    University College London

  • Mina Ryten

    Co-PI (Core Leadership): Team Hardy Team Wood

    University College London

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    Benjamin O’Callaghan, PhD

    Key Personnel: Team Hardy

    University College London