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SpatialBrain.org – a platform to view integrated data from Wade-Martins Laboratory of Molecular Neurodegeneration

By Peter kilfeather, Jia Hui Khoo, Katherina Wagner, Han Liang, Maria Claudia Caiazza, Yanru An, Xingju Zhang, Xiaoyan Chen, Natalie Connor-Robson, Zhouchun Shang, Richard Wade-Martins, PhD
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Output Details

Description
An open repository to access data and results from spatial and translatome expression profiling of basal dopaminergic neurons in mice (OVX and aging). More information can be viewed in published article Kilfeather & Khoo, et al. (2023) "Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease" Spatial Transcriptomic Analyses: - Cell Type Markers - SN/VTA Markers in Dopaminergic Neurons - Cell Number Changes in Age TRAP Analyses: - Dopaminergic Markers - Dopaminergic Ageing - Alternative Splicing in Dopaminergic Neurons Coming soon: Integration with iPS-derived dopaminergic transcriptomic datasets.
Tags
  • Long-read sequencing
  • Mouse
  • Next generation sequencing
  • Postmortem
  • Spatial transcriptomics
Team
Team Cragg
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

  • User avatar fallback logo

    Peter kilfeather

    External Collaborator

  • User avatar fallback logo

    Jia Hui Khoo

    External Collaborator

  • User avatar fallback logo

    Katherina Wagner

    External Collaborator

  • User avatar fallback logo

    Han Liang

    External Collaborator

  • User avatar fallback logo

    Maria Claudia Caiazza

    Key Personnel: Team Cragg, 

    University of Oxford

  • User avatar fallback logo

    Yanru An

    External Collaborator

  • User avatar fallback logo

    Xingju Zhang

    External Collaborator

  • User avatar fallback logo

    Xiaoyan Chen

    External Collaborator

  • User avatar fallback logo

    Natalie Connor-Robson

    External Collaborator

  • User avatar fallback logo

    Zhouchun Shang

    External Collaborator

  • Richard Wade-Martins, PhD

    Co-PI (Core Leadership): Team Cragg, 

    University of Oxford

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Aligning Science Across Parkinson's
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