Stereotaxic injections into mouse brain and ex-vivo electrophysiology

By Jyoti Gupta and Michael Higley, MD, PhD
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Output Details

Description
This protocol describes the method for injection of α-Synuclin PFF and monomer into the mouse brain. The second part of the protocol describes preparation of acute slices from these mice and whole-cell patch clamp recordings.
Identifier (DOI)
10.17504/protocols.io.n2bvjn7qpgk5/v1
Tags
  • Alpha-synuclein
  • Animal
  • Electrophysiology
  • Ex Vivo
  • Injections
  • Pre-formed fibrils (PFFs)
Team
Team Biederer
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

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