Systemic AAV administration through retro-orbital injection

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Description

Adeno-associated viruses (AAVs) are popular tools for gene delivery to animal models. Natural and engineered AAVs can even achieve widespread transduction of target organs through systemic delivery. Fast (<3 minute per mouse) and reproducible transduction through systemic AAV delivery can be achieved with retro-orbital injection. This protocol describes how to systemically deliver AAVs via the retro-orbital sinus.

Identifier (DOI)

10.17504/protocols.io.36wgqnw73gk5/v1

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