The role of α-synuclein in exocytosis

Description

The pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein α-synuclein (αsyn). αSyn has been shown to regulate several cellular processes, however, its normal function remains poorly understood. In this review, we will specifically focus on its role in exocytosis.

Identifier (DOI)

10.1016/j.expneurol.2023.114668

Tags

Alpha-synuclein
Neurotransmitters
Parkinson's disease
Review
Synaptic vesicle exocytosis

Team

Team Edwards

Program

Collaborative Research Network

Theme

Circuitry and Brain-Body Interactions

Meet the Authors

Gautam Runwal, PhD

Key Personnel: Team Edwards,

University of California, San Francisco
Robert Edwards, MD

Lead PI (Core Leadership): Team Edwards,

University of California, San Francisco

The role of α-synuclein in exocytosis

Output Details

Meet the Authors

Gautam Runwal, PhD

Robert Edwards, MD

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