Unilateral 6-hydroxydopamine lesion mouse model of Parkinson’s disease

Output Details

To generate a mouse model of Parkinson's disease, unilateral injection of 6-OHDA(6-hydroxydopamine) into the medial forebrain bundle (MFB) was performed. Three to four weeks later, a drug-free cylinder test was used to assess the extent of lesion.
Tags
  • 6-OHDA
  • Animal
  • Animal models
  • In Vivo
  • Mouse
  • Parkinson's disease

Meet the Authors

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    Cristina Alcacer,

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    Shenyu Zhai, PhD

    Key Personnel: Team Surmeier

    Northwestern University