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Dataset for Article “Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum”

By Andrew (AJ) Miller, ManHua Zhu, Ryan Kovaleski, Baran Demir, Talia Lerner, PhD
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Output Details

Description
This is the primary dataset for the article by Miller-Hansen et al "Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum"
Identifier (DOI)
10.5281/zenodo.20087244
Tags
  • Acetylcholine
  • Dopamine
  • Electrophysiology
  • Fiber photometry
  • In Vivo
  • Motor learning
  • Mouse
Discovery Team
Team Edwards
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

Related Research

Code for Miller-Hansen article “Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum”

This is the code generated by Miller-Hansen for analyzing output from Guppy.

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Thalamus orchestrates local acetylcholine-dependent dopamine release in the learning striatum

Thalamic input can trigger dopamine release in the striatum during motor learning, likely reflecting action vigor rather than motor error. Changes in this mode of dopamine release may contribute to motor and non-motor symptoms of PD.

View Article

Quantifying Acetylcholinesterase activity in striatal brain tissue with DTNB assay

This protocol describes the steps to measure acetylcholinesterase (AChE) activity in mouse striatal brain tissue, including how to store tissue samples, extract AChE and obtain Michaelis-Menten like plots to measure the rate of AChE activity.

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Aligning Science Across Parkinson's
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