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Development and characterization of a non-human primate model of disseminated synucleinopathy

By Alberto J Rico, Almudena Corcho, Julia Chocarro Garcia, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, Patricia Arnaiz, José Luis Lanciego
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Output Details

Description
In this study, the performance and biodistribution of the retrogradely-spreading AAV9-SynA53T vector was evaluated in the NHP brain. Conducted intraparenchymal deliveries of viral suspensions in the left putamen gave rise to a disseminated synucleinopathy in a circuit-specific basis.
Tags
  • In Vivo
  • Non-human primate
Discovery Team
Team Vila
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

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    Alberto J Rico

    External Collaborator

  • User avatar fallback logo

    Almudena Corcho

    External Collaborator

  • User avatar fallback logo

    Julia Chocarro Garcia

    External Collaborator

  • User avatar fallback logo

    Goiaz Ariznabarreta

    External Collaborator

  • User avatar fallback logo

    Elvira Roda

    External Collaborator

  • User avatar fallback logo

    Adriana Honrubia

    External Collaborator

  • User avatar fallback logo

    Patricia Arnaiz

    External Collaborator

  • User avatar fallback logo

    José Luis Lanciego

    External Collaborator

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Aligning Science Across Parkinson's
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