EMD-45297

By Minghao Chen, PhD and James Hurley
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Output Details

Description
#### Structure of human ULK1C:PI3KC3-C1 supercomplex
Tags
  • Autophagy
  • Human
  • Other
  • PI3KC3-C1 complex
  • Structural biology
Team
Team Hurley
Program
Collaborative Research Network
Theme
PD Functional Genomics

Meet the Authors

Related Research

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

ULK1C and PI3KC3-C1 are key players in macroautophagy initiation, with cryo-EM revealing a direct physical interaction between them. Here, authors suggest the mechanism for autophagy initiation.

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EMD-40658

Structure of human ULK1 complex core (2:1:1 stoichiometry)

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EMD-40735

Structure of human ULK1 complex core (2:2:2 stoichiometry) of the ATG13(450-517) mutant

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