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ENS Quantification

By Bryan B. Yoo, Jessica A. Griffiths, Peter Thuy-Boun, Kelly Weldon, Collin Challis, Michael J. Sweredoski, Taren M. Thron, Gil Sharon, Annie Moradian, Gregory Humphrey, Qiyun Zhu, Justin Shaffer, Dennis W. Wolan, Pieter C. Dorrestein, Rob Knight, Viviana Gradinaru, PhD, Sarkis Mazmanian
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Output Details

Description

Labelled enteric neurons in living mice with recombinant adeno-associated viruses (rAAVs) expressing fluorescent proteins, and used tissue clearing techniques to enhance visualization of intact GI tissue.

Identifier (DOI)
10.1101/2021.04.12.439539
Tags
  • Mouse
Team
Team Sulzer
Program
Collaborative Research Network
Theme
Neuro-Immune Interactions

Meet the Authors

  • User avatar fallback logo

    Bryan B. Yoo

    External Collaborator

  • User avatar fallback logo

    Jessica A. Griffiths

    External Collaborator

  • User avatar fallback logo

    Peter Thuy-Boun

    External Collaborator

  • User avatar fallback logo

    Kelly Weldon

    External Collaborator

  • User avatar fallback logo

    Collin Challis

    External Collaborator

  • User avatar fallback logo

    Michael J. Sweredoski

    External Collaborator

  • User avatar fallback logo

    Taren M. Thron

    External Collaborator

  • User avatar fallback logo

    Gil Sharon

    External Collaborator

  • User avatar fallback logo

    Annie Moradian

    External Collaborator

  • User avatar fallback logo

    Gregory Humphrey

    External Collaborator

  • User avatar fallback logo

    Qiyun Zhu

    External Collaborator

  • User avatar fallback logo

    Justin Shaffer

    External Collaborator

  • User avatar fallback logo

    Dennis W. Wolan

    External Collaborator

  • User avatar fallback logo

    Pieter C. Dorrestein

    External Collaborator

  • User avatar fallback logo

    Rob Knight

    External Collaborator

  • Viviana Gradinaru, PhD

    Lead PI (Core Leadership): Team Gradinaru, 

    California Institute of Technology

  • Sarkis Mazmanian

    Co-PI (Core Leadership): Team Sulzer,  Team Gradinaru, 

    California Institute of Technology

Related Research

Dataset for Article “Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum” by Brill-Weil et al

Dopaminergic neuron axons have GABAARs and nAChRs that influence DA release. GABAAR antagonism enhances nAChR activity, while picrotoxin inhibits nAChRs, revealing GABAARs' role in regulating nicotinic input onto DA axons.

View Dataset

GRIN lens implant (1 mm) Protocol

This is the standard 1 mm GRIN lens implant protocol for Rodrigues-Vaz and Athalye et al, 2025.

View Protocol

Perfusion and Histology Rodrigues-Vaz and Athalye et al, 2025

This is the standard protocol for perfusion and histology of brain slices for Rodrigues-Vaz and Athalye et al, 2025.

View Protocol
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Aligning Science Across Parkinson's
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