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Fabrication and calibration of multi-fiber arrays to monitor dopamine release in the mouse striatum

Output Details

We have developed a multi-fiber photometry approach to monitor dopamine release with sub-millimeter spatial resolution and sub-second temporal resolution at over 50 locations simultaneously throughout the striatum in awake, behaving mice expressing a fluorescent sensor. This protocol includes the array fabrication and pre-implant mapping steps.
Tags
  • Equipment
  • Fiber photometry
  • In Vivo
  • Mouse
  • Multi-electrode array

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Aligning Science Across Parkinson's
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