Generation of a Mouse Model of GBA1-Associated Parkinson’s Disease Using CBE Treatment

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Description

The protocol describes in detail how to induce GCase loss of function in mice using CBE treatment. Mice exhibit severe motor symptoms accompanied by neuroinflammation after four weeks of daily CBE injections using this protocol.

Identifier (DOI)

10.17504/protocols.io.36wgq2bj3gk5/v1

Tags

Animal

Discovery Team

Team Vangheluwe

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Tae-Un Han

External Collaborator

Generation of a Mouse Model of GBA1-Associated Parkinson’s Disease Using CBE Treatment

Output Details

Meet the Authors

Tae-Un Han

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