ASAP supports three programs and serves as a member of multiple consortia to advance research for the benefit of the global Parkinson’s disease community.
ASAP shares the impact that our initiative, network, and supported programs have had on providing new insights into Parkinson’s disease. Discover news, interviews, awards, and annual impact.
ASAP is dedicated to facilitating a research environment where meaningful collaboration, research-enabling resources, and data sharing provides the answers we need to understand, diagnose, and treat Parkinson’s disease. Discover our open science philosophy.
ASAP is committed to developing and openly sharing research outputs, including data, code, protocols, and key lab materials, to help the scientific community build upon existing work.
Lead PI (Core Leadership): Team Harper,
Harvard University
Key Personnel: Team Harper,
During nutrient stress, macroautophagy is employed to degrade cellular macromolecules. The authors' results reveal that autophagic turnover prioritizes membrane-bound organelles for proteome remodeling during nutrient stress.
Protocol for adding a 3X HA tag to TMEM192 gene in human cells using CAS9 and recombination template is described for H9 ES AAVS1-NGN2 cells.
Method that allows the staining of intact Golgi using GolgiTracker for subsequent flow cytometry analysis.
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