Golgi immunopurification (Golgi-IP) for subcellular lipid profiling

Output Details

The Golgi is a membrane-bound organelle that is central to protein and lipid processing, sorting and secretion in the cell. Despite its critical cellular function, there has been challenges to quantitatively assess Golgi lipid profiles. To overcome this hurdle, we developed a rapid harvesting and purification method using immunoprecipitation (Golgi-IP). This protocol provides details for preparing Golgi-IP lipidomics samples.

Tags
  • Golgi apparatus
  • Immunoprecipitation
  • Lipidomics

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