In Silico analysis links the NSL complex to Parkinson’s disease and the mitochondria – Protein-protein interaction data to functional enrichment analysis

Output Details

This bioinformatics approach has been taken to investigate the interactome of the NSL complex, to unpick its relevance to PD progression. The mitochondrial interactome of the NSL complex has been built, mining 3 separate repositories: PINOT, HIPPIE and MIST, for curated, literature-derived protein-protein interaction (PPI) data.
Tags
  • Bioinformatics
  • GWAS
  • LRRK2
  • Mitochondria
  • PD progression
  • VPS35

Meet the Authors

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    Katie Kelly, PhD

    Key Personnel: Team Hardy

    University College London

  • Patrick Lewis, PhD

    Collaborating PI: Team Hardy

    Royal Veterinary College

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    Helene Plun-Favreau, PhD

    Collaborating PI: Team Hardy

    University College London

  • Claudia Manzoni, PhD

    Key Personnel: Team Hardy

    University College London