Microscopy-based bead protein-protein interaction assay.

Output Details

This protocol describes how to perform microscopy-based bead protein-protein interaction assay with GST- or mCherry-tagged proteins as baits and fluorescently-tagged proteins as preys. The protocol requires to have purified proteins and allows to monitor protein-protein interaction in an equilibrium state. The fluorescent signal can be quantified.
Tags
  • Biochemistry
  • Other
  • Recombinant

Meet the Authors

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    Elisabeth Holzer, MSc

    Key Personnel: Team Hurley

    Max Perutz Labs