Neuronal transdifferentiation from human primary adult fibroblasts

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Description

This is a protocol for the direct conversion of human primary fibroblasts into neurons using a combination of transcription factor- and small molecule-based approach. The majority of converted neurons showing characteristics of cortical glutamatergic neurons.

Identifier (DOI)

10.17504/protocols.io.j8nlko6d5v5r/v1

Tags

Differentiation
Primary culture
Transdifferentiation

Team

Team Harper

Program

Collaborative Research Network

Theme

PD Functional Genomics

Meet the Authors

Ching Chieh (Ian) Chou, PhD

Key Personnel: Team Harper,

Stanford University
Judith Frydman

Co-PI (Core Leadership): Team Harper,

Stanford University

Neuronal transdifferentiation from human primary adult fibroblasts

Output Details

Meet the Authors

Ching Chieh (Ian) Chou, PhD

Judith Frydman

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