pCDH1-CMV-FIP200-V44D/V314D/L324D/R543D/R548D-mCherry-Hygro

View Published Lab Material

Output Details

Description
Lentiviral expression vector encoding FIP200 mutant-mCherry
Team
Team Hurley
Program
Collaborative Research Network
Theme
PD Functional Genomics

Related Research

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex

Authors determine cryo-EM structure of human ULK1C core and its complex with PI3KC3-C1. ULK1C core undergoes a rearrangement from 2:1:1 to 2:2:2 stoichiometry, suggesting a structural mechanism for autophagy initiation.

View Article

Electrophysiological validation of striatal neurons and dopamine neurons in D1-Cre, A2a-Cre, D1-FlpO, A2a-FlpO, DAT-FlpO transgenic mice

Electrophysiology dataset from whole-cell recordings from murine striatal spiny projection and midbrain dopaminergic neurons from acute slices prepared from knock-in transgenic mouse lines: D1-Cre- A2a-Cre- D1-FlpO- A2a-FlpO- DAT-FlpO.

View Dataset

Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons

To enable precise genetic targeting of key neuronal populations in the basal ganglia, we generated and characterized five knock-in mouse lines: Drd1-Cre, Adora2a-Cre, Drd1-FlpO, Adora2a-FlpO, and DAT-FlpO.

View Article
View More Outputs