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pCHMWS-hATP13A4_A356V-IRES-Puro​

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Output Details

Description
transfer plasmid for lentiviral vector production expressing Hs ATP13A4 A356V mutant
Discovery Team
Team Vangheluwe
Program
Collaborative Research Network
Theme
PD Functional Genomics

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Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission

Polyamines are crucial for brain function. ATP13A4 is the main polyamine transporter in astrocytes, impacting astrocyte morphology, synapse formation, and neurodevelopment. Mutations in ATP13A4 are linked to neurodevelopmental disorders.

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pCHMWS-hATP13A4_A356V-Twinstrep-Flag-IRES-Puro

transfer plasmid for lentiviral vector production expressing Hs ATP13A4 A356V mutant with Twinstrep-Flag tag

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AAV-gfaABC1D-Lamp1-TurboID-HA

Using the gfaABC1D promoter expressing Lamp1-TurboID fusion protein

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Aligning Science Across Parkinson's
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