Key Personnel: Team Hurley,
Max F. Perutz Laboratories
Mitophagy maintains mitochondrial health by degrading damaged mitochondria. TBK1 adaptors NAP1 and SINTBAD regulate OPTN-driven mitophagy initiation and NDP52-driven progression, balancing pathway activity for efficient functioning.
Plasmid for expression of human ATG9-V836A mutant in mammalian cells
Associated with preprint: https://doi.org/10.1101/2023.06.26.546565
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