Motor cortical regions have undergone evolutionary expansion and specialization from rodents to primates. Studying these regions in non-human primates (NHPs) is relevant to understanding motor control in NHP models of movement disorders.
The para-STN is a poorly-defined region near critical DBS targets for PD. Here, we construct anatomical maps of para-STN and STN in multiple species using novel molecular markers in conjunction with FISH and light-sheet microscopy.
This protocol details standard operating procedure (SOP) for systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in non-human primates.
