Our Year in Review: Insights, outcomes, and highlights that shaped 2025. Read the full report!
Aligning Science Across Parkinson's Logo Text

Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology Code: Goralsth/Spatial-transcriptomicSpatial transcriptomics Code: Spatial-transcriptomics-reveals-molecular-dysfunction-associated-with-cortical-Lewy-pathology

By Thomas Goralski, MSc, Michael Henderson, PhD, Lindsay Meyerdirk, MSc, Libby Breton, MSc, Laura Brasseur, Kevin Kurgat, BA, Daniella DeWeerd, Lisa Turner, Katelyn Becker,, Daniel J. Newhouse, Marie Adams
View Published Code

Output Details

Description
Code repository for Goralski, et., al., 2024. "Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology" (https://doi.org/10.1038/s41467-024-47027-8)
Tags
  • Human
  • Mouse
  • Spatial transcriptomics
Team
Team Biederer
Program
Collaborative Research Network
Theme
Circuitry and Brain-Body Interactions

Meet the Authors

  • User avatar fallback logo

    Thomas Goralski, MSc

    Key Personnel: Team Biederer, 

    Van Andel Institute

  • Michael Henderson, PhD

    Co-PI (Core Leadership): Team Biederer,  Team Lee, 

    Van Andel Institute

  • Lindsay Meyerdirk, MSc

    Key Personnel: Team Biederer,  Team Lee, 

    Van Andel Institute

  • User avatar fallback logo

    Libby Breton, MSc

    Key Personnel: Team Biederer, 

    Van Andel Institute

  • User avatar fallback logo

    Laura Brasseur

    Key Personnel: Team Biederer, 

    Van Andel Institute

  • User avatar fallback logo

    Kevin Kurgat, BA

    Key Personnel: Team Biederer, 

    Van Andel Institute

  • User avatar fallback logo

    Daniella DeWeerd

    Key Personnel: Team Biederer, 

    Van Andel Institute

  • User avatar fallback logo

    Lisa Turner

    External Collaborator

  • User avatar fallback logo

    Katelyn Becker,

    External Collaborator

  • User avatar fallback logo

    Daniel J. Newhouse

    External Collaborator

  • User avatar fallback logo

    Marie Adams

    External Collaborator

Related Research

Progressive vulnerability of cortical synapses in α-synucleinopathy

α-Synuclein aggregation is linked to progressive loss of intracortical VGLUT1+ excitatory synapses, spares VGLUT2+ long-range synapses, and impairs cortical excitatory transmission.

View Article

western blot data of ‘A new selection strategy to enrich dopaminergic neurons facilitates comparisons between patient iPSC-derived lines’

western blot data of 'A new selection strategy to enrich dopaminergic neurons facilitates comparisons between patient iPSC-derived lines'

View Dataset

HT707

Induced pluripotent stem cell

View Lab Material
View More Outputs
Aligning Science Across Parkinson's
Powered by  GDPR Cookie Compliance
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.